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An Introduction to Open, Accessible Microbial Genome Data Analysis

This faculty and researcher development program is a live webinar series hosted by ASM Department of Education and co-hosted by the (KBase) as part of the (MICROnet).

With advancing technologies and ever-increasing availability of data, current researchers and researchers-in-training need computational biology skills early in their careers. The data analysis modules of MICROnet introduce data science skills to researchers and educators using KBase, a free, online, open-access data analysis platform that requires no coding experience or computational resources. 

The first in a 2-part series will cover analysis of microbial isolate genomes—from raw sequence data through to data publication—in a modularized format that uses KBase’s reproducible notebook workflows. The second of the 2-part series, From Sample to MAG: Identifying and Characterizing Microbes in the Environment, will be held Sept. 2–Oct. 14, 2025. 

MICROnet also offers community-developed teaching resources that enable student exploration of microbiome research questions. Instructors create teaching workflows based on ‘omics data concepts (e.g., genomics, metagenomics, metabolic modeling and transcriptomics) often taught in courses from general biology to microbiology to bioinformatics. Leveraging KBase, these modularized workflows can be quickly customized to any course and result in student-authored data publications in . 

Participants in this professional development series will: 
  • Learn new skills with a supportive community of ASM members.
  • Use the free, online, open-access KBase platform for data analysis and publication.
  • Learn how to apply and adapt microbial isolate genome analysis workflows for their own research and/or teaching courses. 
  • Follow and apply the FAIR (findable, accessible, interoperable, reusable) data principles in research, including best practices for sample metadata and data publishing.
Tuesday, March 25, 12–1:30 p.m. ET | Introduction to Microbial Isolate Genome Analysis and KBase
Session 1 provides an overview of the microbial genome analysis workflow and introduces the free and open-access KBase platform to participants. After an orientation to the platform’s general layout, participants will be introduced to the example dataset and analysis tools used during the course.

Tuesday, April 8, 12–1:30 p.m. ET | Genome Assembly and Annotation
Session 2 introduces quality control (trimming and filtering) of raw sequence data and prepares the data for genome assembly. Then, the session will cover different types of assembly, including a comparison between the short- and long-reads tools available in KBase and introduce tools used for microbial genome annotation.

Tuesday, April 29, 12-1:30 p.m. ET | Taxonomic and Functional Analysis
Session 3 will taxonomically identify the genomes and generate a phylogenetic tree and begin exploring how to use the annotated genomes for functional analysis, including introducing tools in KBase to build metabolic models or predict function.

Tuesday, May 6, 12-1:30 p.m. ET | °®¶¹´«Ã½ Resource Announcement Templates for Isolates
Session 4 puts the full workflow together and maps the process to the MRA templates available in KBase: quality control, assembly, annotation, genus and species identification and predictive function, as requirements for an MRA data publication. The series will wrap up with an overview of FAIR data principles and best practices for data management and publication using KBase.

Course Learning Goals 

Having completed all sessions, participants will be able to:
  • Analyze their own data or public data and build their custom analysis workflows in KBase for microbial isolate genomes. 
  • Use the KBase Narrative to prepare a microbial isolate genome for a data publication in ASM’s °®¶¹´«Ã½ Resource Announcements. 

Format

  • Attendance at the live events is required. The facilitators will be working in real-time during the webinar sessions. The first hour of each webinar will be recorded in case of conflicts. 
  • During the live sessions, there will be an interactive tutorial for the first hour, followed by 30 minutes for break-out groups for further hands-on practice, application and trouble shooting. 
  • Participants will receive a link to the recording after the live event. The recording will be available until Jan. 31, 2026.

Eligibility

  • This series is for researchers and educators at any career stage.
  • While coding skills and advanced knowledge of bioinformatics are not required, it is recommended that participants have a general understanding of biological concepts and microbiology. 
  • For undergraduate educators based in the U.S., there are additional opportunities to support instructor training and undergraduate research within MICROnet. We will discuss these opportunities during the sessions.

Registration Details

  • ASM members (all categories except supporting members or student member): $250 for the 4-part series.
  • ASM student members: $150 for the 4-part series.
  • Non-members (non-members or ASM supporting members): $350 for the 4-part series.
  • No refunds and no discounts will be given. 
  • All registrants will receive a link to the recording after the live event and will have access until Jan. 31, 2026.

Presenters

Contact Information

ASM Education, education@asmusa.org